Below are some references from Dr Mamta Sohal's presentation during the recent National Education Session. These references can help you with any information on management of pregnancy in sickle cell

Eugene Oteng-Ntim et al; Pregnancy outcome in patients with sickle cell disease in the
UK – a national cohort study comparing sickle cell anaemia (HbSS) with HbSC disease; British Journal of Haematology, 2015, 169, 129–137

Julia van Campen et al; A novel non-invasive prenatal sickle cell disease test for all
at-risk pregnancies; British Journal of Haematology, 2020, 190, 119–124

Eugene Oteng-Ntim et al ; Management of sickle cell disease in pregnancy. A British
Society for Haematology Guideline; British Journal of Haematology, 2021, 194, 980–995

Laure Jospeh et al ;Hydroxycarbamide (HU), Sickle Cell Disease and Pregnancy, a Multicentric Retrospective Study; Blood (2016) 128 (22) : 1309.

Kato, G. J. et al. (2018) Sickle cell disease Nat. Rev. Dis. Primers doi:10.1038/nrdp.2018.10

Faculty of Sexual and Reproductive Healthcare of the Royal College of
Obstetricians and Gynaecologists. UK medical eligibility criteria for contraceptive
use (UK MEC). [cited 2021 Jul 8]. Available from:

Standards for the Clinical Care of Adults with Sickle Cell Disease in the UK; 2nd addition 2018. Sickle Cell Society

Oteng-Ntim E, Meeks D, Seed P et al. Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: Systematic review and meta-analysis. Blood 2015; 125: 3316–3325

Knight M, Bunch K, Tuffnell D et al, on behalf MBRRACE-UK. Saving Lives, Improving Mothers’ Care - Lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2016-18. Oxford: National Perinatal Epidemiology Unit, University of Oxford.2020. Available from  (accessed 13 January 2021)

Royal College of Obstetricians and Gynaecologists. Management of Sickle Cell Disease in Pregnancy. RCOG Green top Guideline 61, 2011

Anaesthetic management of patients with sickle cell disease in obstetrics BJA Education Vol. 22Issue 3p87–93Published in issue: March, 2022 K. Stoddard, M. Sohal, R. Bedson